2012年8月31日金曜日

BevacizumabとPFS、OS

JCOのreview記事によくまとめられています。

http://jco.ascopubs.org/content/early/2012/08/26/JCO.2012.43.6931.full.pdf+html


Overall, bevacizumab increases the risk of grade 3 to 5 AEs and SAEs without apparent effect on OS and only moderate impact on PFS (Fig 1).

ということで、早く、biomarkerが分かるといいです。

さらに、

Although we, as a society, are committed to investing heavily in valuable treatments against cancer, that investment is not a blank check, and a serious discussion among all stakeholders is needed regarding the appropriate balance of costs and effectiveness of treatments for advanced cancer.

とても大事なことだと思います。